Research

The mission of the Katsevich Lab is to unravel the regulatory wiring of the human genome, with the ultimate goal of understanding the molecular basis of human diseases. For example, mapping enhancers to their target genes helps uncover disease mechanisms:

To this end, we develop novel statistical methodologies to analyze the data produced by cutting-edge single cell genomics assays, such as single cell CRISPR screens and single cell multi-omics data (publications). These methodologies span an interconnected set of statistical research areas:

We back these methods with statistical theory and implement them in high-quality softwares aimed at biologists.